GO:0035279 biological_process mRNA cleavage involved in gene silencing by miRNA
| PAG Title | GO:0035279 biological_process mRNA cleavage involved in gene silencing by miRNA |
| PAG ID | TAX022799 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism. |
| Species | Homo sapiens |
| nCoCo Score | 0 |
| Base PAG ID | TAX022799 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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